
GraphPad Prism
Statistical analysis and scientific graphing purpose-built for researchers
About GraphPad Prism
GraphPad Prism is statistical analysis and graphing software built for scientific research, especially in biology, pharmacology, and medicine. It organizes data into eight purpose-built table types, guides users to an appropriate test with assumption checklists, and makes curve fitting such as dose-response analysis a one-click task. Graphs and results update automatically when data changes, and Prism Cloud lets teams share and review projects.
Pros & Cons
Pros
- Curve fitting and dose-response analysis are faster than in any general-purpose stats package
- Data table types prevent common mistakes by matching data layout to valid tests
- Publication-quality graphs come out of the same tool as the statistics
- Assumption checklists and plain-language help make test choice less error-prone
- Academic and student pricing are well below corporate rates
Cons
- Not suited to large survey datasets or advanced multivariate modeling
- No scripting language for reproducible automated pipelines
- Subscription required for updates; perpetual licenses get no upgrades
- Corporate pricing is high for individual consultants
Key Features
One-Click Nonlinear Regression
Select an equation and Prism fits the curve, reports parameters, draws the fit, and interpolates unknowns, including dose-response curves.
Purpose-Built Data Tables
Eight table types (XY, column, grouped, contingency, survival, parts of whole, multiple variables, nested) that steer you toward valid analyses.
Guided Test Selection
Each analysis includes an assumptions checklist and effect size reporting in plain language.
ANOVA and Mixed Models
One-, two-, three-way and multifactor ANOVA, with mixed-effects models for repeated measures with missing data.
Survival and Logistic Regression
Kaplan-Meier survival, Cox regression, and simple and multiple logistic regression.
Sample Size and Power Analysis
Estimate the sample size needed for an expected effect or the smallest detectable effect.
Publication-Quality Graphs
Journal-ready exports with control over resolution, color space, dimensions, and automatic significance stars.
Prism Cloud
Share, view, and collaborate on Prism projects with role-based workspace access.
Live-Linked Results
Edits to data or analysis choices update results, graphs, and layouts instantly.
Pricing
- For enrolled students
- Statistical analysis
- Scientific graphing
- Prism Cloud
- Statistical analysis
- Scientific graphing
- Data visualization
- Prism Cloud
- Corporate price: $520/year
- Everything in Standard
- Multiple variables classic analyses
- K-means and hierarchical clustering
- Multifactor ANOVA
- In-table formulas
- Corporate price: $675/year
- Short-term projects
- Standard feature set
- Pro available at $75/month
- Prism 11 license
- No upgrades included
- No group management or collaboration features
- Corporate perpetual: $3,200
- Everything in Pro
- SSO and SCIM provisioning
- Advanced collaboration
- Premium support
Best For
Pharmacology and Dose-Response
Fit EC50/IC50 curves and compare treatments with one-click nonlinear regression.
Bench Biology Experiments
Analyze grouped experiments with ANOVA and multiple comparisons and graph them for publication.
Preclinical Survival Studies
Run Kaplan-Meier survival analysis and Cox regression on animal or cohort data.
Lab-Wide Collaboration
Share projects through Prism Cloud so PIs can review analyses without exchanging files by email.
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