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GraphPad Prism

GraphPad Prism

Statistical analysis and scientific graphing purpose-built for researchers

Founded
1989
Starting Price
$142
Category
Analytics & BI
Company Size
Part of Dotmatics (500-1000 employees)
Last updated October 7, 2026

About GraphPad Prism

GraphPad Prism is statistical analysis and graphing software built for scientific research, especially in biology, pharmacology, and medicine. It organizes data into eight purpose-built table types, guides users to an appropriate test with assumption checklists, and makes curve fitting such as dose-response analysis a one-click task. Graphs and results update automatically when data changes, and Prism Cloud lets teams share and review projects.

Pros & Cons

Pros

  • Curve fitting and dose-response analysis are faster than in any general-purpose stats package
  • Data table types prevent common mistakes by matching data layout to valid tests
  • Publication-quality graphs come out of the same tool as the statistics
  • Assumption checklists and plain-language help make test choice less error-prone
  • Academic and student pricing are well below corporate rates

Cons

  • Not suited to large survey datasets or advanced multivariate modeling
  • No scripting language for reproducible automated pipelines
  • Subscription required for updates; perpetual licenses get no upgrades
  • Corporate pricing is high for individual consultants

Key Features

One-Click Nonlinear Regression

Select an equation and Prism fits the curve, reports parameters, draws the fit, and interpolates unknowns, including dose-response curves.

Purpose-Built Data Tables

Eight table types (XY, column, grouped, contingency, survival, parts of whole, multiple variables, nested) that steer you toward valid analyses.

Guided Test Selection

Each analysis includes an assumptions checklist and effect size reporting in plain language.

ANOVA and Mixed Models

One-, two-, three-way and multifactor ANOVA, with mixed-effects models for repeated measures with missing data.

Survival and Logistic Regression

Kaplan-Meier survival, Cox regression, and simple and multiple logistic regression.

Sample Size and Power Analysis

Estimate the sample size needed for an expected effect or the smallest detectable effect.

Publication-Quality Graphs

Journal-ready exports with control over resolution, color space, dimensions, and automatic significance stars.

Prism Cloud

Share, view, and collaborate on Prism projects with role-based workspace access.

Live-Linked Results

Edits to data or analysis choices update results, graphs, and layouts instantly.

Pricing

Student Standard
$142/year
  • For enrolled students
  • Statistical analysis
  • Scientific graphing
  • Prism Cloud
Personal Standard (Academic)
$260/year
  • Statistical analysis
  • Scientific graphing
  • Data visualization
  • Prism Cloud
  • Corporate price: $520/year
Personal Pro (Academic)
$360/year
  • Everything in Standard
  • Multiple variables classic analyses
  • K-means and hierarchical clustering
  • Multifactor ANOVA
  • In-table formulas
  • Corporate price: $675/year
Monthly Standard
$50/month
  • Short-term projects
  • Standard feature set
  • Pro available at $75/month
Perpetual (Academic)
$1,600/one-time
  • Prism 11 license
  • No upgrades included
  • No group management or collaboration features
  • Corporate perpetual: $3,200
Enterprise
Custom
  • Everything in Pro
  • SSO and SCIM provisioning
  • Advanced collaboration
  • Premium support

Best For

Pharmacology and Dose-Response

Fit EC50/IC50 curves and compare treatments with one-click nonlinear regression.

Bench Biology Experiments

Analyze grouped experiments with ANOVA and multiple comparisons and graph them for publication.

Preclinical Survival Studies

Run Kaplan-Meier survival analysis and Cox regression on animal or cohort data.

Lab-Wide Collaboration

Share projects through Prism Cloud so PIs can review analyses without exchanging files by email.

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